Use of statins to inhibit formation of osteoclasts

A method for inhibiting the formation of osteoclasts comprising administering a therapeutically effective amount of a statin to a mammal in need thereof as well as pharmaceutical compositions, kits for containing such compositions comprising a statin or a method of treating or preventing a disease s...

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Bibliographische Detailangaben
Hauptverfasser: BARAGI VIJAYKUMAR MAHALINGAPPA, PETERS BRANDON R, DEVALARAJA RADHIKA, RENKIEWICZ RICHARD RAYMOND
Format: Patent
Sprache:eng
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Zusammenfassung:A method for inhibiting the formation of osteoclasts comprising administering a therapeutically effective amount of a statin to a mammal in need thereof as well as pharmaceutical compositions, kits for containing such compositions comprising a statin or a method of treating or preventing a disease state selected from the group consisting of: osteoporosis, Paget's disease, osteolysis, hypercalcemia of malignancy, osteogenesis imperfecta, osteoarthritis, alveolar bone loss, side effects of immunosuppressive therapy, and side effects of chronic glucocorticoid use by inhibiting the formation of osteoclasts comprising administering a therapeutically effective amount of a statin to a mammal in need thereof.