Methods involving the use of capG as a diagnostic marker and methods for the identification of capG modulators for the treatment and prevention of osteoporosis and related disease states

The present invention relates to the identification of capG as a critical enzyme in the process of RANKL-induced osteoclast-activation. The present invention includes modulators of capG and assays for the identification of such modulators, as well as the use of such modulators in the treatment and p...

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Bibliographische Detailangaben
1. Verfasser:	MCATEE C. PATRICK
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the identification of capG as a critical enzyme in the process of RANKL-induced osteoclast-activation. The present invention includes modulators of capG and assays for the identification of such modulators, as well as the use of such modulators in the treatment and prevention of osteoporosis and related disease states.