Snake toxin and its use as pharmaceutical

The present invention relates to a peptide having the amino acid sequence 1 Leu Thr Cys Leu Asn Cys Pro Glu Met Phe 1 5 10 Cys Gly Lys Phe Gln Ile Cys Arg Asn Gly 15 20 Glu Lys Ile Cys Phe Lys Lys Leu His Gln 25 30 Arg Arg Pro Leu Ser Trp Arg Tyr Ile Arg 35 40 Gly Cys Ala Asp Thr Cys Pro Val Gly Ly...

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Bibliographische Detailangaben
Hauptverfasser:	UTKIN YURI, METHFESSEL CHRISTOPH, TSETLIN VIKTOR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a peptide having the amino acid sequence 1 Leu Thr Cys Leu Asn Cys Pro Glu Met Phe 1 5 10 Cys Gly Lys Phe Gln Ile Cys Arg Asn Gly 15 20 Glu Lys Ile Cys Phe Lys Lys Leu His Gln 25 30 Arg Arg Pro Leu Ser Trp Arg Tyr Ile Arg 35 40 Gly Cys Ala Asp Thr Cys Pro Val Gly Lys 45 50 Pro Tyr Glu Met Ile Glu Cys Cys Ser Thr 55 60 Asp Lys Cys Asn Arg 65 or alleles derived therefrom, or peptides containing essential parts of the peptide (I), to a process for the preparation thereof and the use thereof for producing a pharmaceutical for the treatment of diseases of which therapy is possible through inhibition of the alpha7-nACh receptor, in particular the treatment of cancer such as small cell lung carcinoma.