System for co-culturing bacteria and eukaryotic cells

The present invention is directed to an apparatus that can be used for co-culturing bacteria and eukaryotic cells. The apparatus allows the bacteria to be grown under steady state conditions and then perfused over the eukaryotic cells. The invention also includes a variety of methods for studying th...

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Bibliographische Detailangaben
Hauptverfasser: MALIN GENNADY, PAOLETTI LAWRENCE C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to an apparatus that can be used for co-culturing bacteria and eukaryotic cells. The apparatus allows the bacteria to be grown under steady state conditions and then perfused over the eukaryotic cells. The invention also includes a variety of methods for studying the attachment and invasion of host eukaryotic cells by bacteria.