cDNA clones encoding human G protein gamma subunits

Nucleic acid molecules encoding human gamma2, gamma3, gamma4, gamma5, gamma7, gamma10 and gamma11 subunits are provided. Subunit polypeptides are also provided. In addition, method of detecting mutated forms of human gamma subunit and altered levels of human gamma subunit are provided. Methods of id...

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Hauptverfasser: KUNSCH CHARLES A, ROBISHAW JANET D
Format: Patent
Sprache:eng
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Zusammenfassung:Nucleic acid molecules encoding human gamma2, gamma3, gamma4, gamma5, gamma7, gamma10 and gamma11 subunits are provided. Subunit polypeptides are also provided. In addition, method of detecting mutated forms of human gamma subunit and altered levels of human gamma subunit are provided. Methods of identifying antagonists and agonists of the interaction of a betagamma ligand with its receptor are also provided.