Nasal delivery of apomorphine in combination with glycol derivatives

Intranasal delivery compositions and methods for the delivery of dopamine receptor agonists are provided which are effective for the treatment14 of sexual dysfunction in a mammal without causing substantial intolerable adverse side effects to the mammal, in particular adverse nasal effects. Nasally...

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Bibliographische Detailangaben
Hauptverfasser: ROMEO VINCENT D, AHMED SHAMIN, DEMEIRELES JORGE, LIU TIANQUING, BEHL CHARANJIT, SILENO ANTHONY, ACHARI RAJA
Format: Patent
Sprache:eng
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Zusammenfassung:Intranasal delivery compositions and methods for the delivery of dopamine receptor agonists are provided which are effective for the treatment14 of sexual dysfunction in a mammal without causing substantial intolerable adverse side effects to the mammal, in particular adverse nasal effects. Nasally administered compositions for treating sexual dysfunction in a mammal are also provided which include a therapeutically effective amount of a dopamine receptor agonist which has been dispersed in a system to improve its solubility and/or stability.