Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof;wherein R1 R2, R4 and X1 are defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolog...

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Bibliographische Detailangaben
Hauptverfasser:	Miltz, Wolfgang, Tichkule, Ritesh Bhanudasji, Patel, Tajesh, Wälchli, Rudolf, Sandham, David Andrew, Rajagopalan, Srinivasan, Roehn, Till, Labbe-Giguere, Nancy, Chen, Xin, Orain, David, Thoma, Gebhard, Bushaboina, Mallesh, Culshaw, Andrew James, Cheung, Atwood Kim, Hurley, Timothy Brian
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof;wherein R1 R2, R4 and X1 are defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.