Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a target cell

Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a target cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the target cell, the...

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Hauptverfasser: Lee, Jong Won, Kim, Jay S, Kim, HoWon J, Kwon, Ick Chan, Yang, Yoo Soo, Yoon, Hong Yeol, Kim, Sun Hwa, Kim, In-San
Format: Patent
Sprache:eng
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Zusammenfassung:Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a target cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the target cell, the therapeutic compound ultimately being internalized by the target cell via endocytosis. The target cell may be a cancer cell.