X-ray image data monitoring and signaling for patient safety

Techniques are provided for x-ray image data monitoring and signaling for patient safety. A methodology implementing the techniques according to an embodiment includes integrating energy associated with a received x-ray pulse at an array of pixels. The method also includes multiplexing a readout of the integrated energy from the array of pixels, as analog signals, into channels, and performing analog to digital conversion of the analog signals of the channels into digital signals. The method further includes generating an error indicator in response to determining that a calculated mean of the digital signals is either greater than an upper threshold value associated with saturation or less than a lower threshold value associated with underexposure. The method further includes transmitting the error indicator over a Universal Serial Bus, to an imaging system, to terminate transmission of further x-ray pulses.