Crystalline forms of a neuroactive steroid

This invention relates to crystalline forms of anhydrous Compound (1) and pharmaceutical compositions thereof. Also disclosed herein are methods of making crystalline solid forms of Compound (1), and methods of using the crystalline forms of Compound (1) and pharmaceutical compositions thereof for m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuang, Shanming, Li, Tianrui
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to crystalline forms of anhydrous Compound (1) and pharmaceutical compositions thereof. Also disclosed herein are methods of making crystalline solid forms of Compound (1), and methods of using the crystalline forms of Compound (1) and pharmaceutical compositions thereof for modulating GABA activity (e.g., positive allosteric modulation of GABA activity) and treating CNS-related disorders.