AT2R antagonists and uses thereof

AT2R antagonists and uses thereof

This invention provides certain piperidine compounds as AT2R antagonists, e.g., compounds of formula (I):or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and X are as defined herein, pharmaceutical compositions thereof, and methods of using the same to treat pain associated with AT2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Garcia Paredes, Maria Cristina, Sher, Emanuele, Chen, Zhaogen, Erickson, Jon Andre, Winneroski, Leonard Larry, Beauchamp, Thomas James, Conner, Scott Eugene, Lineswala, Jayana Pankajkumar, Thapa, Bishnu
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention provides certain piperidine compounds as AT2R antagonists, e.g., compounds of formula (I):or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and X are as defined herein, pharmaceutical compositions thereof, and methods of using the same to treat pain associated with AT2R activity.