Algorithm for mix-size depalletizing

A system and method for identifying a box to be picked up by a robot from a stack of boxes. The method includes obtaining a 2D red-green-blue (RGB) color image of the boxes and a 2D depth map image of the boxes using a 3D camera. The method employs an image segmentation process that uses a simplified mask R-CNN executable by a central processing unit (CPU) to predict which pixels in the RGB image are associated with each box, where the pixels associated with each box are assigned a unique label that combine to define a mask for the box. The method then identifies a location for picking up the box using the segmentation image.