Use for preventing and treating myeloid-derived suppressor cell-related diseases

The present invention relates to an antibody or an antigen-binding fragment thereof specifically binding to CD66c which is expressed in myeloid-derived suppressor cell (MDSC) and a use thereof, and specifically to an antibody or an antigen-binding fragment thereof specifically binding to CD66c, a ph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Song, Hyung-Geun, Hong, Jeong Won, Yoon, Sangsoon, Kim, Soseul, Ji, Gil Yong
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to an antibody or an antigen-binding fragment thereof specifically binding to CD66c which is expressed in myeloid-derived suppressor cell (MDSC) and a use thereof, and specifically to an antibody or an antigen-binding fragment thereof specifically binding to CD66c, a pharmaceutical composition or a diagnosing composition including the same. The anti-CD66c antibody of the present invention can be used usefully for the treatment of various diseases by targeting MDSC which can induce the immunosuppression.