Methods of purifying antibodies

A method of isolating an antibody is disclosed. The method comprises contacting a hydrophobic chelator, a non-ionic detergent and metal ions so as to generate an aggregate comprising the hydrophobic chelator, the detergent and the metal ions; and contacting the aggregate with a medium comprising the...

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Bibliographische Detailangaben
Hauptverfasser: Sheves, Mordechai, Patchornik, Guy, Cohen, Margalit (Maggie), Namboothiri, Irishi N. N, Howard, Assaf
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method of isolating an antibody is disclosed. The method comprises contacting a hydrophobic chelator, a non-ionic detergent and metal ions so as to generate an aggregate comprising the hydrophobic chelator, the detergent and the metal ions; and contacting the aggregate with a medium comprising the antibody under conditions that allow partitioning of the antibody into the aggregate. Kits for isolating the antibody are also disclosed.