Use of C-type natriuretic peptide variants to treat skeletal dysplasia

Use of C-type natriuretic peptide variants to treat skeletal dysplasia

The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth ve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bullens, Sherry, Wendt, Daniel J, Bunting, Stuart, Yap, Clarence, Chou, Tianwei, Okhamafe, Augustus O, Price, Christopher P
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.