Inhibitors of HIF-2α and methods of use thereof

Inhibitors of HIF-2α and methods of use thereof

The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gal, Balint, Yu, Kai, Liu, Dongdong, Mata, Guillaume, Epplin, Matthew, Mailyan, Artur Karenovich, Hardman, Clayton, Lawson, Kenneth Victor, Rosen, Brandon Reid, Podunavac, Ma{hacek over (s)}a, Drew, Samuel Lawrie, Powers, Jay Patrick, Fournier, Jeremy, Leleti, Manmohan Reddy, Beatty, Joel Worley
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present disclosure is directed to compounds that are inhibitors of HIF-2α having a structure according to Formula I, and compositions containing those compounds. Methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.