Sequencing and high resolution imaging

Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. There have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy or polynucl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burns, Norman, Liu, Niandong, Furtado, Manohar R, Staker, Bryan P, Fang, Rixun, Owens, Windsor
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. There have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy or polynucleotide sequencing applications.