Compositions, systems, and methods for base diversification

Described herein are methods of modifying or editing a target nucleic acid such as methods that edit adenine to cytosine, thymine, or guanine. Compositions and systems for modifying or editing a target nucleic acid are also described. Methods, compositions and systems described herein may be used fo...

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Bibliographische Detailangaben
Hauptverfasser: Hummel, Aaron, Kim, Yongjoo
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Described herein are methods of modifying or editing a target nucleic acid such as methods that edit adenine to cytosine, thymine, or guanine. Compositions and systems for modifying or editing a target nucleic acid are also described. Methods, compositions and systems described herein may be used for generating allelic diversity.