Sustained release formulations of Crocus sativus

The present invention is related to the novel oral dosage form for sustained release of crocin-1, a active constituent of Crocus sativus extract or fraction and a process for preparing the same wherein the extract is wet-granulated using excipients, biodegradable polymers and/or non-biodegradable po...

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Mehak, Vishwakarma, Ram, Singh, Rohit, Bharate, Sandip Bibishan, Bharate, Sonali Sandip, Rani, Sarita, Kumar, Vikas, Kumar, Ajay
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention is related to the novel oral dosage form for sustained release of crocin-1, a active constituent of Crocus sativus extract or fraction and a process for preparing the same wherein the extract is wet-granulated using excipients, biodegradable polymers and/or non-biodegradable polymers alone or in combination. The said formulations are useful for the treatment of chronic inflammatory diseases wherein NLRP3 inflammasome is involved.