Methods and systems for reversibly consummating fluidic connections

Provided herein is a method for sterile fluid transfer. A first array of conduits may be disposed in a first compartment having a planar face with an array of cavities, each containing a cannular protrusion fluidly connected to a conduit. A second array of conduits may be disposed in a second compar...

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Bibliographische Detailangaben
Hauptverfasser: Stone, Michael Anthony Disimoni, Jones, Samuel Isidor, Pap, Gabor, Hiles, Adam Luke, Page, Matthew Edwin, Olf, Ryan, Cummings, Thomas Felix Martin, Wilson, Spencer Ryan, Cantrell, Aaron Garden, Bohner, Gergo
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein is a method for sterile fluid transfer. A first array of conduits may be disposed in a first compartment having a planar face with an array of cavities, each containing a cannular protrusion fluidly connected to a conduit. A second array of conduits may be disposed in a second compartment having its own planar face with an array of surface cannular protrusions, each fluidly connected to a conduit in the second array. The method may include sterilizing the lumens of each conduit-protrusion pair; snugly juxtaposing the two planar faces to form an array of steam-tight chambers; introducing a sterilizing gas into the chambers; expelling the sterilizing gas from the chambers; moving each cannular protrusion towards its facing surface protrusion to reversibly form a fluid connection therebetween, while the chamber remains externally sealed, and transferring a fluid across at least one fluidic connection.