Broad-spectrum antimicrobial, biocompatible and preservative-free functionalized fullerenes ophthalmic solution with reactive oxygen species scavenging and advanced targeting, penetration, and hydration

The present invention introduces an ophthalmic solution containing halo-fullerenes. When the spherical fullerene carbon cages are functionalized with halogens, the resulting halo-fullerenes demonstrate sustained antimicrobial activity. Fullerenes are also characterized by unique electron properties that impart antioxidant capabilities as free radical scavengers. Nonetheless, far smaller than ocular tissue cells, halo-fullerenes are biocompatible-and capable of penetrating intricate barriers, like the cornea and conjunctiva, with potential to achieve greater efficacy and symptom relief in chronic dry eye than conventional treatments. With remarkable surface area, halo-fullerenes also allow customization and possess a unique molecular architecture for broader applications. This multifunctional solution thus imparts antimicrobial activity, antioxidative protection, molecular lubrication, and shielding from external irritants while penetrating dense ocular structures. Without the need for antibiotic additives or preservatives, the invention can offer an effective, safe option for dry eye treatment, prophylaxis in contact lens solutions, and post-surgical care.