Systems, methods, and media for identifying and responding to malicious files having similar features

Systems, methods, and media for identifying and responding to malicious files having similar features are provided. More particularly, in some embodiments, systems for identifying and responding to malicious files having similar features are provided, the systems comprising: a memory; and a hardware processor coupled to the memory and configured to: receive feature information extracted from a file, wherein the feature information includes at least two of static feature information, environmental feature information, and behavioral feature information; create clusters based on the feature information; determine if a file corresponding to one of the clusters is malicious; and report to a plurality of endpoints that other files corresponding to the one of the clusters is malicious.