Device and method for isolating extracellular vesicles from biofluids

A device and method for isolating extracellular vesicles from biofluids is disclosed. A nanoporous silicon nitride membrane is provided with a tangential flow of biofluid. A pressure gradient through the nanoporous silicon nitride membrane facilitates capture of extracellular vesicles from the tange...

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Bibliographische Detailangaben
Hauptverfasser: Chung, Henry Hung Li, McGrath, James Lionel, Lucas, Kilean Scott
Format: Patent
Sprache:eng
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Zusammenfassung:A device and method for isolating extracellular vesicles from biofluids is disclosed. A nanoporous silicon nitride membrane is provided with a tangential flow of biofluid. A pressure gradient through the nanoporous silicon nitride membrane facilitates capture of extracellular vesicles from the tangential flow vector of biofluid. Reversal of the pressure gradient results in the release of the extracellular vesicles for subsequent collection.