Monoclonal antibody specifically binding to LAG-3 and use thereof

A monoclonal antibody or an antigen-binding fragment thereof according to an embodiment of the present invention can bind to lymphocyte-activation gene 3 (LAG-3) including a heavy chain variable region and a light chain variable region and inhibit the activity thereof. Thus it is expected to be usef...

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Bibliographische Detailangaben
Hauptverfasser: Park, Bum-Chan, Choi, Yunseon, Song, Youngja, Lee, Sang Pil, Yoo, Seok Ho, Park, Jae Eun, Park, Young Woo, Lee, Dong Jung, Shin, Ji-Young, Kim, Yeung-chul, Yoon, Sunha, Baek, Gisun, Lee, Ji Su
Format: Patent
Sprache:eng
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Zusammenfassung:A monoclonal antibody or an antigen-binding fragment thereof according to an embodiment of the present invention can bind to lymphocyte-activation gene 3 (LAG-3) including a heavy chain variable region and a light chain variable region and inhibit the activity thereof. Thus it is expected to be useful for the development of immunotherapeutic agents for various disorders that are associated with LAG-3.