Immunogenic antigen identification from a pathogen and correlation to clinical efficacy

Embodiments of the disclosure concern methods of identifying whether or not antigens from a particular pathogen are immunogenic, including the order of their immunogenicity. Other embodiments concern correlations between attributes of T cells and their clinical efficacy, such as mathematical represe...

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Hauptverfasser: Aguayo-Hiraldo, Pailbel, Tzannou, Ifigeneia, Leen, Ann Marie, Vera Valdes, Juan F
Format: Patent
Sprache:eng
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Zusammenfassung:Embodiments of the disclosure concern methods of identifying whether or not antigens from a particular pathogen are immunogenic, including the order of their immunogenicity. Other embodiments concern correlations between attributes of T cells and their clinical efficacy, such as mathematical representations thereof.