Systems and methods for generating three-dimensional measurements using endoscopic video data

Presented herein are systems and methods for performing three-dimensional measurements of a surgical space using two-dimensional endoscopic images. According to an aspect, video data taken from an endoscopic imaging device can be used to generate a three-dimensional model of the surgical space represented by the video data. In one or more examples, two-dimensional images from the video data can be used to generate a three-dimensional model of the surgical space. In one or more examples, the one or more two-dimensional images of the surgical space can include a fiducial marker as part of the image. Using both the depth information and a size reference provided by the fiducial marker, the systems and methods herein can generate a three-dimensional model of the surgical space. The generated three-dimensional model can then be used to perform a variety of three-dimensional measurements in a surgical cavity in an accurate and efficient manner.