Aryl alkynamide derivatives

[Problem] A compound which is useful as a STING inhibitor is provided.[Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as...

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Bibliographische Detailangaben
Hauptverfasser:	Yamashita, Yumi, Kamikawa, Akio, Kuriwaki, Ikumi, Maeda, Junko, Hamaguchi, Wataru, Kitamura, Kai, Seo, Ryushi, Kakefuda, Kenichi, Negoro, Kenji, Ciavarri, Jeffrey
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	[Problem] A compound which is useful as a STING inhibitor is provided.[Means for Solution] The present inventors have found aryl alkynamide derivatives having an inhibitory action on STING. The aryl alkynamide derivatives of the present invention have an inhibitory action on STING and can be used as an agent for treating an autoimmune disease, a neurodegenerative disease, a type I interferonopathy and/or other STING-mediated disease.