Advanced genome editing

Methods of genetically modifying microorganisms using advanced genome editing are disclosed. Methods of modifying the genome of these microorganisms for point mutations, deletions, and DNA insertions are also disclosed. Further, inhibiting expression of genes without manipulating the genome of the m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dietzel, Kevin Lee, Li, Xuezhi, Kealey, James
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods of genetically modifying microorganisms using advanced genome editing are disclosed. Methods of modifying the genome of these microorganisms for point mutations, deletions, and DNA insertions are also disclosed. Further, inhibiting expression of genes without manipulating the genome of the microorganism is disclosed. In some cases, the microorganism can be a methylotroph, e.g., a methanotroph.