Dual targeting and therapeutic nanoparticle for treating renal fibrosis

The subject invention pertains to compositions and methods for making and use of metal-based coated nanoparticles. The metal-based, PEG-coated nanoparticles of the invention comprise folic acid molecules on their surface exercise dual functionality by specifically targeting renal tubule cells and tr...

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Bibliographische Detailangaben
Hauptverfasser: Chan, Cecilia Ka Wing, Choi, Chung Hang Jonathan, Lau, Yun Wong James
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The subject invention pertains to compositions and methods for making and use of metal-based coated nanoparticles. The metal-based, PEG-coated nanoparticles of the invention comprise folic acid molecules on their surface exercise dual functionality by specifically targeting renal tubule cells and treating renal fibrosis.