Functionalized n-acetylgalactosamine analogs
Embodiments of the present application relate to functionalized N-acetylgalactosamine-analogs, methods of making, and uses of the same. In particular, mono or trivalent N-acetylgalactosamine analogs may be prepared by utilizing a wide variety of linkers containing functional groups. These functional...
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| creator | Zou, Mufa Guan, Xiaoyang Lau, Aldrich N. K Zhao, Gang Poon, Wing C Yu, David Yao, Yun-Chiao Du, Gengyu Zheng, Xiaoling Zou, Ruiming |
| description | Embodiments of the present application relate to functionalized N-acetylgalactosamine-analogs, methods of making, and uses of the same. In particular, mono or trivalent N-acetylgalactosamine analogs may be prepared by utilizing a wide variety of linkers containing functional groups. These functionalized N-acetylgalactosamine-analogs may be used in the preparation of targeted delivery of oligonucleotide-based therapeutics. |
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| subjects | CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS |
| title | Functionalized n-acetylgalactosamine analogs |
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