Multiple object collision avoidance based on centralized coordination of vehicle operations

A computer-implemented method performed by a centralized coordinated vehicle guidance system may include: obtaining analytics data for a plurality of vehicles or objects centrally communicating with or detected by the centralized coordinated vehicle guidance system; detecting, based on the analytics data, a predicted collision event involving multiple pairs of the plurality of vehicles or objects; determining trajectory adjustment information for a first vehicle of the plurality of vehicles involved in the collision event; and outputting the trajectory adjustment information to cause the first vehicle to modify its trajectory.