Polymerase enzyme from 9°N

The present invention relates to a polymerase enzyme from 9° N with improved ability to incorporate reversibly terminating nucleotides. The enzyme comprising mutations in the motif A region. The invention also relates to methods of using such enzymes as well as a kit with such polymerases.

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Bibliographische Detailangaben
Hauptverfasser: Olejnik, Jerzy, Delucia, Angela
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a polymerase enzyme from 9° N with improved ability to incorporate reversibly terminating nucleotides. The enzyme comprising mutations in the motif A region. The invention also relates to methods of using such enzymes as well as a kit with such polymerases.