Antibody therapies for human immunodeficiency virus (HIV)

Featured are PGT121 variant antibodies or fragments thereof, which can be administered, e.g., as antibody therapies for treating human immunodeficiency virus (HIV) infection. In particular, featured are methods of treating subjects infected with HIV and/or blocking HIV infections in subjects at risk...

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Bibliographische Detailangaben
Hauptverfasser: Clark, Rutilio H, Siska, Christine C, Ketchem, Randal R, Barouch, Dan H, Kerwin, Bruce A, Floyd, Julee A, Gillespie, Alison J, Rogers, Richard S, Shaver, Jeremy M
Format: Patent
Sprache:eng
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Zusammenfassung:Featured are PGT121 variant antibodies or fragments thereof, which can be administered, e.g., as antibody therapies for treating human immunodeficiency virus (HIV) infection. In particular, featured are methods of treating subjects infected with HIV and/or blocking HIV infections in subjects at risk of HIV transmission using the PGT121 variant antibodies or fragments thereof.