Ursodeoxycholic acid derivatives as HDAC inhibitors for the treatment of polycystic diseases

Ursodeoxycholic acid derivatives as HDAC inhibitors for the treatment of polycystic diseases

The present invention relates to compounds derived from ursodeoxycholic acid of formula (I), to methods for obtaining same, as well as the use thereof in the treatment of polycystic diseases, particularly autosomal dominant polycystic liver disease, autosomal dominant polycystic kidney disease, or a...

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Bibliographische Detailangaben
Hauptverfasser: Banales Asurmendi, Jesus Maria, Cossio Mora, Fernando Pedro, Caballero Camino, Francisco Javier, Rivilla De La Cruz, Ivan, Santos Laso, Alvaro, Esteller Badosa, Manel, Garcia Marin, Jose Juan, Bujanda Fernandez De Pierola, Luis
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to compounds derived from ursodeoxycholic acid of formula (I), to methods for obtaining same, as well as the use thereof in the treatment of polycystic diseases, particularly autosomal dominant polycystic liver disease, autosomal dominant polycystic kidney disease, or autosomal recessive polycystic kidney disease.