Combination therapy intravaginal rings

The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of dapivirine in combination with either an antimicrobial compound or a contraceptive to a human. The present invention also provides methods of blocking D...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brimer, Andrew Nathan, Boyd, Peter John James, Holt, Jonathon Daryll, Nuttall, Jeremy Peter, Devlin, Brid, Malcolm, Karl, Fetherston, Susan Margaret
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of dapivirine in combination with either an antimicrobial compound or a contraceptive to a human. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, methods of preventing unintended pregnancy in a female human, and methods of preparing intravaginal rings.