Therapeutic inhibition affinity of copper (II) complex and their diazenyl pyridinone heterocyclic ligands against SARS-CoV2

Therapeutic inhibition affinity of copper (II) complex and their diazenyl pyridinone heterocyclic ligands against SARS-CoV2

Methods of using copper (II) complexes of Formula I to prevent and/or treat coronavirus infections, such as SARS-CoV-2 infections, are provided. In Formula I, Y is NO2 or CH3 and X is a C1 to C20 hydrocarbon which is optionally substituted. The copper (II) complexes bind to an inactivate proteins th...

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Hauptverfasser: Alsulami, Ahlam Ibrahim, Al-Zaydi, Khadijah M, A. Hussein, Mostafa A. Hussien
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Methods of using copper (II) complexes of Formula I to prevent and/or treat coronavirus infections, such as SARS-CoV-2 infections, are provided. In Formula I, Y is NO2 or CH3 and X is a C1 to C20 hydrocarbon which is optionally substituted. The copper (II) complexes bind to an inactivate proteins that are necessary for the virus to successfully establish an infection and reproduce.