Crispr enzymes and systems

The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Wolf, Yuri I, Zhang, Feng, Minakhin, Leonid, Koonin, Eugene, Shmakov, Sergey, Semenova, Ekaterina, Konermann, Silvana, Abudayyeh, Omar O, Joung, Julia, Gootenberg, Jonathan S, Severinov, Konstantin, Makarova, Kira S, Lander, Eric S
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.