Flavonoid polyphenol drug self-emulsifying composition, preparation method therefor, pharmaceutical composition thereof and application thereof

A flavonoid polyphenol drug self-emulsifying composition based on a flavonoid polyphenol drug-phospholipid complex being used as an intermediate, the composition comprising a flavonoid polyphenol drug-phospholipid complex, an oil phase, an emulsifier and a co-emulsifier, the flavonoid polyphenol dru...

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Hauptverfasser: Zhang, Yun, Ye, Jun, Gao, Yue, Xia, Xuejun, Dong, Wujun, Liu, Lu, Wang, Bangyuan, Feng, Yu, Liao, Hengfeng, Yang, Yanfang, Liu, Zhihua, Zhou, Junzhuo, Liu, Yuling
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Sprache:eng
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Zusammenfassung:A flavonoid polyphenol drug self-emulsifying composition based on a flavonoid polyphenol drug-phospholipid complex being used as an intermediate, the composition comprising a flavonoid polyphenol drug-phospholipid complex, an oil phase, an emulsifier and a co-emulsifier, the flavonoid polyphenol drug comprising one or more selected from baicalein, proanthocyanidin, quercetin, curcumin and resveratrol. The described self-emulsifying composition has the beneficial effects of good stability, a high amount of drug loading, high bioavailability, and so on.