C3-binding agents and methods of use thereof

C3-binding agents and methods of use thereof

The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yan, Duey, Dana Yen Mei, Zhai, Wenwu, Tang, Jie, Yin, Yiyuan, Higbee, Jared Martin, Liu, Zhonghao
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.