Vehicle cooler with passenger cabin access

A vehicle assembly is provided that affords multiple access points to a cold-storage container. The vehicle assembly includes a vehicle having a passenger cabin and a cargo area adjacent the passenger cabin. A cold-storage container is disposed in the cargo area and includes a first opening providing access from the cargo area to an interior of the cold-storage container, and a second opening providing access from the passenger cabin into the interior. In various aspects, the vehicle may be a pickup truck, where the cold-storage container is located in a cargo bed. A header portion of the cargo bed can include an access door configured to selectively provide a passageway between the cargo bed and the interior of the passenger cabin. The passenger cabin may include an access panel that selectively provides entry to the passageway and into the cold-storage container.