JAK kinase inhibitor compounds for treatment of respiratory disease

The invention provides compounds of formula (I):wherein X isand the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using...

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Bibliographische Detailangaben
Hauptverfasser:	Rapta, Miroslav, Benjamin, Noah, Jacobsen, John R, Fatheree, Paul R, Sullivan, Steven D. E, Smith, Cameron, Van Orden, Lori Jean, Dabros, Marta, Fleury, Melissa, Beausoleil, Anne-Marie, Jiang, Lan, Colson, Pierre-Jean, Thalladi, Venkat R, Brandt, Gary E. L, Fass, Gene Timothy
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides compounds of formula (I):wherein X isand the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat respiratory diseases, and processes and intermediates useful for preparing such compounds.