5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same

5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same

The present embodiments are directed, in part, to 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, such as those of Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor,...

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Bibliographische Detailangaben
Hauptverfasser: Yuan, Catherine C. K, Miskowski Daubert, Tamara Ann, Kargbo, Robert Borbo, Speerschneider, Aimee Crombie, Herr, Robert Jason, Romero, Donna, Yamashita, Dennis Shinji, Pitis, Philip Michael, Liu, Guodong, Hawkins, Michael John
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present embodiments are directed, in part, to 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, such as those of Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinson's Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof.