Anti-human LAG-3 monoclonal antibody and use thereof

Disclosed in the present invention are an antibody targeting LAG-3, a preparation method therefor and the use thereof. In particular, disclosed in the present invention is a novel monoclonal antibody targeting LAG-3. Also disclosed in the present invention is a method for the preparation of the mono...

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Bibliographische Detailangaben
Hauptverfasser: Song, Ningning, Duan, Qing, Yang, Tatchi Teddy, Wang, Peng, Wang, Yuandong, Shao, Xiaohui, Wu, Jian, Bian, Xiaojiao, Wang, Qian, Huang, Yajun, Liu, Lile, Xu, Lina, Wei, Peipei, Wang, Meiling
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed in the present invention are an antibody targeting LAG-3, a preparation method therefor and the use thereof. In particular, disclosed in the present invention is a novel monoclonal antibody targeting LAG-3. Also disclosed in the present invention is a method for the preparation of the monoclonal antibody. The monoclonal antibody of the present invention is capable of binding LAG-3 antigens with high specificity, and has very high affinity and significant activities such as anti-tumor activity.