Process control systems and associated monoflanges

In accordance with an example, a process control system includes a fluidic line having a longitudinal axis and including a fluidic connection. The fluidic connection has an axis angled relative to the longitudinal axis of the fluidic line. The process control system includes a primary block valve having an inlet port and an outlet port. The inlet port is coupled to the fluidic connection. The process control system includes a monoflange including a male portion forming an inlet port and including an external threaded surface. The monoflange includes an outlet and a flanged interface surrounding the outlet port of the monoflange. The monoflange includes a bleed port. The monoflange includes a bleed valve adapted to control fluid flow from the bleed port and a secondary block valve adapted to control fluid flow from the outlet port. The external threaded surface of the male portion threadably engages the outlet port of primary block valve.