NADPH oxidase inhibitors, pharmaceutical composition comprising the same, and application thereof

NADPH oxidase inhibitors, pharmaceutical composition comprising the same, and application thereof

The present disclosure relates to a compound of Formula I, or a geometric isomer, enantiomer, diastereomer, racemate, atropisomer, pharmaceutically acceptable salt, prodrug or solvate thereof. The present disclosure further relates to a composition comprising the compound of Formula (I). The compoun...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Syaulan S, Lee, Kuang Yuan, Fan, Yu-Shiou, Liu, Meng Hsien, Wang, Chiung Wen, Hsu, Mei-Chi, Jiang, Yan-Feng
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure relates to a compound of Formula I, or a geometric isomer, enantiomer, diastereomer, racemate, atropisomer, pharmaceutically acceptable salt, prodrug or solvate thereof. The present disclosure further relates to a composition comprising the compound of Formula (I). The compound and the composition described herein can be used to inhibit NADPH oxidase activity.