Phosphoinositide 3-kinase inhibitor with a zinc binding moiety

The invention provides a compound of Formula I,Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetyl...

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Bibliographische Detailangaben
Hauptverfasser: Cai, Xiong, Qian, Changgeng, Lai, Chengjung, Zhai, Haixiao, Bao, Rudi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a compound of Formula I,Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.