Selection of network paths for reliable communications based on network reliability metrics

Systems, devices, and methods are provided for transmitting and retransmitting data. A first message transmitted by a sender computing entity to a receiver computing entity over a first port may exercise a first network path whereas a second message transmitted over a second port may exercise a second network path. A system (e.g., sender computing entity) may determine network reliability metrics for a plurality of network paths. If a system detects data loss (e.g., packet loss) on a first port, a second port may be selected based on network reliability metrics for retransmission of the lost data. A port may for example, be selected for retransmission based on the following criteria: (1) the port has the longest consecutive duration without packet loss and (2) the port has received an acknowledgement for a packet that was sent more recently than the initial transmission of the lost packet.