Systems and methods to optimize imaging settings for a machine vision job

Methods and systems for optimizing one or more imaging settings for a machine vision job are disclosed herein. An example method includes detecting, by one or more processors, an initiation trigger that initiates the machine vision job. The example method further includes, responsive to detecting the initiation trigger, capturing, by an imaging device, a first image of a target object in accordance with a first configuration of the one or more imaging settings. The example method further includes, responsive to capturing the first image of the target object, automatically adjusting, by the one or more processors, the one or more imaging settings to a second configuration that includes at least one different imaging setting from the first configuration; and capturing, by the imaging device, a second image of the target object in accordance with the second configuration of the one or more imaging settings.