Substituted pyrrolo[2,3-d]pyrimidines as Bruton's Tyrosine Kinase inhibitors

Substituted pyrrolo[2,3-d]pyrimidines as Bruton's Tyrosine Kinase inhibitors

The invention relates to compounds of the formula (I) (I) or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined in the specification; to intermediates in the preparation of the compounds, to pharmaceutical compositions comprising the compounds and to use of the compo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Arista, Luca, Hebach, Christina, Machauer, Rainer, Hollingworth, Gregory John, Holzer, Philipp, Vulpetti, Anna, Zoller, Thomas, Imbach-Weese, Patricia, Lorber, Julien, Schmiedeberg, Niko
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention relates to compounds of the formula (I) (I) or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined in the specification; to intermediates in the preparation of the compounds, to pharmaceutical compositions comprising the compounds and to use of the compounds in the treatment of disease.