Pyrrolo-aromatic heterocyclic compound, preparation method therefor, and medical use thereof

The present invention relates to pyrrolo-aromatic heterocyclic compounds, a preparation method therefor and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, an...

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Hauptverfasser: Zheng, Li, Yang, Yan, Yin, Huijun, Yan, Xu, Tian, Weixue, Zong, Libin, Dou, Haoshuai
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to pyrrolo-aromatic heterocyclic compounds, a preparation method therefor and medical use thereof. Particularly, the present invention relates to a compound represented by formula I, a preparation method therefor, a pharmaceutical composition comprising the compound, and use of the compound as a BTK kinase inhibitor. The compound and the pharmaceutical composition comprising same can be used for the treating diseases associated with BTK kinase activity, such as inflammations, autoimmune disorders, and cancers. The definition of each substituent in formula I is the same as that in the description.